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爱游戏官方信誉好:胡萍萍

爱游戏官方信誉好:作者:时间:2022-10-10点击数:

胡萍萍:特聘副教授,硕士生导师。

联系邮箱:huping07@163.com

教育工作经历:

2022. 07-至今,爱游戏官方信誉好,特聘副教授,硕士生导师

2015.09-2022.06,重庆大学爱游戏官方信誉好,讲师,硕士生导师,博士生导师

2014.07-2015.08陆军军医大学第三附属医院胸外科科研助理

2011.09-2013.09美国德克萨斯大学休斯顿健康医学中心联合培养博士

2007.09-2014.06西南大学生命科学学院生物化学与分子生物学理学博士

2003.09-2007.07西南大学生命科学学院生物技术理学学士

主要研究方向为:

心血管疾病的发病机制研究;

承担的代表性科研课题:

1.国家自然科学基金委员会,青年基金项目,81700237,SERCA2 C674的失活与动脉粥样硬化的关系及调控机制,2018-01至2020-12,20万元

2.中国博士后科学基金59批面上资助项目,2016M592623,SERCA2 C674不可逆氧化加速动脉粥样硬化的机制研究,2016-03至2016-12,5万元

3.重庆市博士后科研项目特别资助项目,Xm2015033,碳点标记PC4抗体荧光探针用于肺腺癌淋巴转移的成像研究,2015-11至2016-12,10万元

发表的代表性论文

1.PP H*, SX Luo, XQ Fan, D Li, XY Tong, Macrophage-targeted nanomedicine for the diagnosis and management of atherosclerosis,Front Pharmacol.2022 13:1000316.

2. H Su, Y Mei,SX Luo,HX Wu, Y He,Y Shiraishi,PP Hu*, RA Cohen, X Tong*, Substitution of the SERCA2 Cys674reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation,Br J Pharmacol,2022,179:4778-4791.

3. G Liu, F Wu, H Wu, Y Wang, X Jiang,PP Hu*, X Tong*, Inactivation of cysteine 674 in the sarcoplasmic/endoplasmic reticulum calcium ATPase 2 causes retinopathy in the mouse,Exp Eye Res, 2021, 207:108559.

4. MK Song, SX Chen,PP Hu*, CZ Huang*, J Zhou*, Automated plasmonic resonance scattering imaging analysis via deep learning,Anal Chem, 2021, 93(4): 2619-2626.

5. W Yu, S Li, H Wu,PP Hu*, L Chen, C Zeng*, X Tong*; Endothelial Nox4 dysfunction aggravates atherosclerosis by inducing endoplasmic reticulum stress and soluble epoxide hydrolase,Free Radic Biol Med, 2021,164: 44-57.

6. H Su,PP Hu*, XL Jiang, TT Wu, X Tong*; Multifunctional aggregation-based fluorescent probe for visualizing intracellular calcium dynamic fluctuations,Anal Bioanal Chem, 2020, 412(26): 7187-7194.

7. XL Jiang, JH Liu, YT Que, YM Que,PP Hu*, CZ Huang, X Tong*; Multifunctional single-layered graphene quantum dots used for diagnosis of mitochondrial malfunction-related diseases,ACS Biomater Sci & Eng, 2020, 6(3): 1727-1734.(IF, 4.75)

8. G Liu, F Wu, X Jiang, YM Que, Z Qin,PP Hu*, KS Lee, J Yang, C Zeng*, BD Hammock, X Tong*; Inactivation of SERCA2 cysteine 674 increases blood pressure by induction of endoplasmic reticulum stress and soluble epoxide hydrolase,Br J Pharmacol,2020, 177:1793-1805.

9. W Qi*, M Zhao, Y Fu, H He, X Tian, D Wu, Y Zhang,PP Hu*; Fluorescent detection of uric acid through photoinduced electron transfer using luminol-terbium(III) nanoparticles synthesized via aggregationinduced fluorescence strategy,Dyes and Pigments, 2020, 172:107797.

10. G Liu, SQ Li,PP Hu*, XY Tong*, Altered sarco(endo)plasmic reticulum calcium adenosine triphosphatase 2a content: Targets for heart failure therapy,Diab Vasc Dis Res. 2018, 15(4): 322-335.

11. XJ Lin, XQ Fan, SJ Xiao, Y He, WJ Qi*,PP Hu*,QY Tan, XY Tong and CZ Huang, Multifunctional fluorescent carbon dots inhibit the invasiveness of lung cancer cells,New J. Chem, 2018, 42, 15311-15314.

12. Y Wang*, P Zhang*, CY Ye, WS Fu, H Yuan,PP Hu*, Y Liu, Hexamethylenetetramine: an effective and universal nitrogen-doping reagent to enhance the photoluminescence of carbon nanodots,New J. Chem, 2018, 42, 3519-3525.

13.PP Hu, XJ Wu, AR. Khandelwal, W Yu, Z Xu, L Chen, J Yang, RM Weisbrod, KS Lee, F Seta, BD Hammock, RA Cohen, C Zeng, X Tong*, Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase,Biochim Biophys Acta, 2017, 1863(6):1382-1391.

14.PP Hu, R Morales, C Duran-Aniotz, I Moreno-Gonzalez, U Khan, C Soto*. Role of prion replication in the strain-dependent brain regional distribution of prions.J Biol Chem, 2016, 291(24): 12880-12887.

15.R Morales#*,PP Hu#, C Duran-Aniotz, F Moda, R Diaz-Espinoza, B Chen, J Bravo-Alegria, N Makarava, IV. Baskakov, C Soto*. Strain-dependent profile of misfolded prion protein aggregates.Sci Rep, 2016, 15(6): 20526. (Co-first author)

16.PP Hu, H Liu, SJ Zhen, CM Li, CZ Huang*, Nanosilver-based surface-enhanced Raman spectroscopic determination of DNA methyltransferase activity through real-time hybridization chain reaction.Biosens Bioelectron, 2015, 73(15): 228-233.

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